Recent CIT Publications
- Stark RJ, Schrimpe-Rutledge AC, Codreanu SG, Sherrod SD, McLean JA, Krispinsky LT, Lamb FS. ENDOTHELIAL-DEPENDENT VASCULAR REACTIVITY AFTER CARDIOPULMONARY BYPASS IS ASSOCIATED WITH UNIQUE METABOLOMIC SIGNATURES. Shock. 2024 Nov 1;62(5):656-662.
DOI: - Mouton AJ, Aitken NM, Morato JG, O’Quinn KR, do Carmo JM, da Silva AA, Omoto ACM, Li X, Wang Z, Schrimpe-Rutledge AC, Codreanu SG, Sherrod SD, McLean JA, Stanford JK, Brown JA, Hall JE. Glutamine metabolism improves left ventricular function but not macrophage-mediated inflammation following myocardial infarction. Am J Physiol Cell Physiol. 2024 Sep 1;327(3):C571-C586.
DOI: - Westland MD, Schrimpe-Rutledge AC, Codreanu SG, Sherrod SD, McLean JA, McClain MS, Cover TL. Taurine modulates host cell responses to Helicobacter pylori VacA toxin. Infect Immun. 2024 Aug 13;92(8):e0022424.
DOI: - Pfalzer AC, Shiino S, Silverman J, Codreanu SG, Sherrod SD, McLean JA, Claassen DO. Alterations in Cerebrospinal Fluid Urea Occur in Late Manifest Huntington’s Disease. J Huntingtons Dis. 2024;13(1):103-111.
DOI: - Schalich KM, Buendia MA, Kaur H, Choksi YA, Washington MK, Codreanu GS, Sherrod SD, McLean JA, Peek RM Jr, Acra SA, Townsend SD, Yan F. A human milk oligosaccharide prevents intestinal inflammation in adulthood via modulating gut microbial metabolism. mBio. 2024 Apr 10;15(4):e0029824.
DOI:
See the complete list
Suggested Reading
- Leaptrot KL, May JC, Dodds JN, McLean JA, Ion mobility conformational lipid atlas for highconfidence lipidomics,ÌýNat. CommunÌý2019, 10:985.
DOI:Ìý - Picache JA, Rose BS, Balinski A, Leaptrot KL, Sherrod SD, May JC, McLean JA,ÌýCollision cross section compendium to annotate and predict multi-omic compound identities,ÌýChem SciÌý2019,Ìý10, 983-993.
DOI:Ìý - Schrimpe-Rutledge AC, Codreanu SG, Sherrod SD, McLean JA, Untargeted Metabolomics Strategies – Challenges and Emerging Directions,ÌýJournal of the American Society for Mass SpectrometryÌý2016, 27:1897.
DOI: - Patti GJ, Yanes O, Siuzdak G. Innovation: Metabolomics: the apogee of the omics trilogy. Nat Rev Mol Cell Biol. 2012 Mar 22;13(4):263-9.
DOI:
Patents
- KL Leaptrot, JC May, JA McLean,ÌýMETHODS AND SYSTEMS FOR ION MOBILITY AND MASS ANALYSIS.
- Caprioli R., Wikswo J., McLean J., Skaar E., Norris J.L., Lacy D.B., Sherrod S., Pino J., Gutierrez D., Muszynski N.D., Farrow M. (2020) High-Throughput, Multi-Omics Approach to Determine and Validate De Novo Global Mechanisms of Action for Drugs and Toxins. .
- McLean, J. A., Russell, D. H., Egan, T. F., Ugarov, M. V. and Schultz, J. A. (2010) Multiplex Data Acquisition Modes for Ion Mobility-Mass Spectrometry.
Useful Links/Resources
- Ìýat ¹ú²ú´«Ã½
Our collaborators for advanced statistical modeling and analysis of molecular omics results for basic science, translational, and clinical research projects - (VMIC)
VMIC coordinates and accelerates interdisciplinary scholarship to establish long-lasting resources in microbiome research and education. This effort brings together approximately 300 members (faculty, staff, students) from six ¹ú²ú´«Ã½ schools to understand, translate, and disseminate the principles that shape host-microbiome interactions, microbial genomics and metabolism, intimate symbiotic relationships, virology, epidemiology, statistical modeling, and applications for precision medicine. - Metabolomics Databases/Libraries:
- Open Source Data AnalysisÌýSoftware:

