{"id":4243,"date":"2016-01-25T08:20:56","date_gmt":"2016-01-25T13:20:56","guid":{"rendered":"https:\/\/www.vanderbilt.edu\/vise\/?p=4243"},"modified":"2017-06-27T15:37:04","modified_gmt":"2017-06-27T20:37:04","slug":"joint-bmevise-guest-seminar-an-adaptable-framework-to-extract-abnormal-brain-networks-wednesday-january-27st-1210pm-noon-lunch-sc-5326","status":"publish","type":"post","link":"https:\/\/www.vanderbilt.edu\/vise\/joint-bmevise-guest-seminar-an-adaptable-framework-to-extract-abnormal-brain-networks-wednesday-january-27st-1210pm-noon-lunch-sc-5326\/","title":{"rendered":"Joint BME\/VISE Guest Seminar: An Adaptable Framework to Extract Abnormal Brain Networks. WEDNESDAY January 27st, 12:10pm, Noon lunch. SC 5326."},"content":{"rendered":"
\u00a0Title:<\/span><\/b> An Adaptable Framework to Extract Abnormal Brain Networks<\/span><\/span><\/div>\n
Speaker:<\/span><\/b>\u00a0 Dr. Archana Venkataraman, Postdoctoral Associate, Image Processing and Analysis Group, Department of Radiology & Biomedical Imaging at Yale University<\/span><\/div>\n
Date:<\/span><\/b> ***Wednesday, January 27th<\/sup>\u00a0 ***<\/span><\/div>\n
Time:<\/span><\/b> 12:10pm start<\/span><\/div>\n
Place:<\/span><\/b> Stevenson Center 5326<\/span><\/div>\n
\u00a0<\/b><\/span><\/div>\n
Abstract:<\/span><\/b>\u00a0 <\/b>There is increasing evidence that complex neurological disorders reflect distributed impairments across multiple brain systems. These findings underscore the importance of network-based approaches for functional data. However, network analyses in clinical neuroimaging is largely limited to aggregate measures, which do not pinpoint a concrete etiological mechanism. In contrast, I will present a novel Bayesian framework that captures the underlying topology of the altered functional pathways.\u00a0 <\/b>In the first part of this talk, I will introduce our core framework to extract abnormal network foci from functional MRI data. This model relies on a latent structure, which captures hidden interactions within the brain; the latent variables are complemented by an intuitive likelihood model for the observed neuroimaging measures. The resulting variational EM algorithm produces clinically meaningful results by simultaneously localizing the centers of abnormal activity and the network of altered connectivity. Next, I will address three technical challenges: flexible network topology, multimodal integration and patient-specific analysis. I will demonstrate that our core framework can elegantly be adapted to each of these scenarios and yields novel insights into autism, schizophrenia and epilepsy, respectively. Finally, I will highlight some exciting future applications for our method that revolve around clinical interventions.<\/span><\/div>\n
<\/div>\n
Biography:<\/span><\/b>\u00a0 Dr. Venkataraman is a postdoctoral associate in the Image Processing and Analysis Group at Yale. Her research lies at the intersection of multimodal integration, network modeling and clinical neuroscience. Her main objective is to combine analytical tools, such as probabilistic modeling and network theory, with neuroscientific findings in order to characterize complex processes within the brain. Her methodology has yielded novel insights into autism, schizophrenia and epilepsy, with the long-term goal of informing patient treatment and care. Archana completed her B.S., M.Eng. and Ph.D. in Electrical Engineering at MIT in 2006, 2007 and 2012, respectively. She is a recipient of the CHDI Grant on network models for Huntington’s Disease, the MIT Lincoln Lab campus collaboration award, the NIH Advanced Multimodal Neuroimaging Training Grant, the National Defense Science and Engineering Graduate Fellowship, the Siebel Scholarship and the MIT Provost Presidential Fellowship. <\/span><\/div>\n
\u00a0<\/span><\/div>\n","protected":false},"excerpt":{"rendered":"

\u00a0Title: An Adaptable Framework to Extract Abnormal Brain Networks Speaker:\u00a0 Dr. Archana Venkataraman, Postdoctoral Associate, Image Processing and Analysis Group, Department of Radiology & Biomedical Imaging at Yale University Date: ***Wednesday, January 27th\u00a0 *** Time: 12:10pm start Place: Stevenson Center 5326 \u00a0 Abstract:\u00a0 There is increasing evidence that complex neurological disorders reflect distributed impairments across…<\/p>\n","protected":false},"author":4,"featured_media":4246,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"spay_email":"","jetpack_publicize_message":"","jetpack_is_tweetstorm":false,"jetpack_publicize_feature_enabled":true,"_links_to":"","_links_to_target":""},"categories":[12],"tags":[231],"acf":[],"jetpack_featured_media_url":"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/193\/2019\/03\/19171004\/ViSE_01-27-2016.jpg","jetpack_publicize_connections":[],"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p98pzF-16r","_links":{"self":[{"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/posts\/4243"}],"collection":[{"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/comments?post=4243"}],"version-history":[{"count":3,"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/posts\/4243\/revisions"}],"predecessor-version":[{"id":5788,"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/posts\/4243\/revisions\/5788"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/media\/4246"}],"wp:attachment":[{"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/media?parent=4243"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/categories?post=4243"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/tags?post=4243"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}